Overview of Letrozole
Among the non-steroidal aromatase inhibitors, letrozole has gained great popularity among athletes. The tool is in demand in 65 countries. It blocks aromatase enzymes. The drug is actively used by athletes and bodybuilders.
Letrozole is widely used as a supplement to a steroid cycle to achieve a reduction in estrogen levels, as well as to increase the hormone testosterone. The tool is one of the best of its kind. This makes the drug very popular among bodybuilders.
Studies have proven the high efficacy of Letrozole. The estrogen concentration drops to 97%. A similar result can only be obtained when high doses are taken. By using the recommended amount you can reduce estrogen to 76 or 79%. It is also a very good result.
Due to the low concentration of estrogen, the manifestation of side effects is reduced by taking steroids. The use of the drug by bodybuilders helps increase the synthesis of globulin, follicle-stimulating luteinizing hormones and testosterone.
A non-steroidal aromatase inhibitor has the following effects on the athlete’s body:
- stops negative estrogenic side effects including acne, gynecomastia, flooding, subcutaneous fat deposits;
- eliminates gynecomastia in all manifestations, even in the initial phase of the course;
- helps maintain muscle mass from catabolism after discontinuation of the drug, which often occurs when steroids are discontinued.
The use of Letrozole is appropriate during a course of using androgens and anabolic steroids.
An estrogen blocker such as Tamoxifen or Clomiphene (Clomid) can reduce estrogen-associated anabolic steroid (AAS) side effects, which are sufficient in most cases. These aromatase inhibitors are on the one hand cheaper than Letrozole and on the other hand they have a positive effect on cholesterol levels as they have a similar effect as cholesterol in the liver. Letrozole is used today mainly for the preparation of bodybuilding competitions because, as already mentioned, it promotes fat loss as well as muscle wasting and lowers estrogen levels.
There is a constant rumor in bodybuilding that gynecomastia can be completely eliminated by simple use of Letrozole. However, this should be considered with caution. In case of gynecology you should always consult your doctor.
How to take Letrozole
It is recommended that bodybuilders take about 1-3 milligrams daily at all times. Daily use of even 100 micrograms can slow down the effect of the aromatase enzyme significantly. It is impossible to exceed the recommended doses. Otherwise, the risk of developing negative consequences increases sharply, especially a decrease in sexual desire.
The daily dose for each bodybuilder is always chosen individually. It all depends on experience, the age of the athlete, the duration of use of a non-steroidal aromatase inhibitor, but should not exceed the optimal 1-3 milligrams. A specialist will help you calculate the exact amount of medication. It is recommended to consult a doctor before using drugs. Prolonged use of the drug allows you to slightly adjust the regimen to take this drug and use the drug not every day, but every other day.
Letrozole prevents the work of estrogen synthetase without affecting the cycles of corticosteroids in the body and without leading to the development of abnormalities. It is used in the fight against gynecomastia, to get rid of excess fluid, to normalize blood pressure.
The main direction of classes is to strengthen the muscles, increase the density of muscle tissue. Switch to periods of intense training to improve post-workout recovery. Activation of the body to produce its own endogenous testosterone.
In female bodybuilding, this drug is not used due to its strong effect on hormone balance.
The Letrozole course offers the use of the drug in varying doses. They can change a lot. In post-cycle therapy, the standard remains unchanged. For a week or 10 days, it is recommended to take the standard 2.5 milligrams a day, and then reduce the dose to 0.5 milligrams for the following two or three weeks.
In the medical field, the dosage of the aromatase inhibitor Letrozole is 2.5 mg per day. It has been shown in various clinical trials, but this is already the case with doses of 0.1 to 0.5 mg of 75% suppression of estrogen production.
Letrozole is often used by bodybuilders during doping to counteract estrogenic side effects. Doses are generally much lower than in the medical field, so doses to reduce estrogen-related side effects are 0.25 to 1.25 mg letrozole taken every other day. Due to the active substance, Letrozole has a half-life of more than two days (approximately 50 hours), usually every other day is sufficient.
Side effects of Letrozole
Letrozole effectively blocks estrogen production by replacing protein compounds in aromatize receptors. Due to its high efficacy, the drug should be used with caution – carefully check the dose, frequency and duration of use. Although in sports it may be desirable to increase the level of testosterone in the blood, one should be aware of the side effects. Letrozole can cause a typical picture of estrogen deficiency, including osteoporosis, atrophy, decreased libido, erectile dysfunction, and pain during intercourse.
Possible side effects:
- Articular pain
- Lost appetite
- Increased appetite
- Excess cholesterol in the blood
- Nausea and vomiting
- Abdominal pains
- Hair loss
- Muscle pain
- Bone loss (osteoporosis)
- Water accumulation in arms and legs.
Such adverse phenomena appear only when the athlete exceeds the recommended dose of the drug. If you follow the instructions, there will be no side effects.
The drug is acceptable for uptake in almost all bodybuilders. Specialist supervision is recommended for athletes who have liver problems or individual intolerance to any component of a non-steroidal aromatase inhibitor. When the use of the drug is accompanied by unpleasant sensations, the course should be canceled and a more suitable drug should be chosen.